The Crown of Thorns

Author:,

Publisher:SparkPress

ISBN:1943006741

Total Pages:

Viewed:699

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A thrilling debut in the style of Crichton or A.G. Riddle, Resistant imagines a chilling—and entirely plausible—future where antibiotics don't work, and weaves adventure, romance, and science into a thrilling chase for a cure. In the final battle with drug-resistant bacteria, one woman's blood holds a secret weapon. Rory and her father have survived the antibiotic crisis that has killed millions, including Rory’s mother—but ingenuity and perseverance aren’t their only advantages. When a stoic and scarred young military veteran enters their quiet life, Rory is drawn to him against her better judgment . . . until he exposes the secrets her mother and father kept from her, including the fact that her own blood may hold the cure the world needs, and she is the target of groups fighting to reach it first. When the government comes after Rory, aiming to use her for a cure it can sell to the highest bidder, she’s forced to flee with her father and their new protector. But can she find the new path of human evolution before the government finds her?

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EARTHQUAKE RESISTANT DESIGN OF STRUCTURES

Author:PANKAJ AGRAWAL,MANISH SHRIKHANDE

Publisher:PHI Learning Pvt. Ltd.

ISBN:9788120328921

Total Pages:660

Viewed:1153

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This comprehensive and well-organized book presents the concepts and principles of earthquake resistant design of structures in an easy-to-read style. The use of these principles helps in the implementation of seismic design practice. The book adopts a step-by-step approach, starting from the fundamentals of structural dynamics to application of seismic codes in analysis and design of structures. The text also focusses on seismic evaluation and retrofitting of reinforced concrete and masonry buildings. The text has been enriched with a large number of diagrams and solved problems to reinforce the understanding of the concepts. Intended mainly as a text for undergraduate and postgraduate students of civil engineering, this text would also be of considerable benefit to practising engineers, architects, field engineers and teachers in the field of earthquake resistant design of structures.

The Ongoing Challenge of Antimicrobial Resistance, An Issue of Infectious Disease Clinics of North America, EBook

Author:Richard R. Watkins,Robert A. Bonomo

Publisher:Elsevier Health Sciences

ISBN:0323759440

Total Pages:240

Viewed:1039

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Together with Consulting Editor Dr. Helen Boucher, Drs. Watkins and Bonomo have put together an issue of Infectious Disease Clinics of North America that provides the most current information on antibiotic resistance. Top experts have contributed clinical review articles that address the types of resistance based on drug class as well as emerging therapies and the future of telemedicine in the management of infections. The following topics are covered in this issue: The changing role of the clinical microbiology laboratory in defining resistance in gram-negatives; Extended-spectrum β-lactamase-producing Enterobacteriaceae infections; Multidrug-resistant bacteria in the community; Resistance to polymyxins; Resistance in Vancomycin-resistant enterococci; Resistance to newer β-lactamase inhibitors; Antibiotic-resistant infections in the immunocompromised host; Emerging therapies for MRSA infections; Drug-resistant tuberculosis; Aminoglycoside resistance; The role of antibiotic stewardship and telemedicine in the management of MDR infections; and Emerging issues in antifungal resistance. Readers will have the current information they need to better manage antibiotic-resistant infections in patients.

Creep-Resistant Steels

Author:Fujio Abe,Torsten-Ulf Kern,R Viswanathan

Publisher:Elsevier

ISBN:1845694015

Total Pages:700

Viewed:534

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Creep-resistant steels are widely used in the petroleum, chemical and power generation industries. Creep-resistant steels must be reliable over very long periods of time at high temperatures and in severe environments. Understanding and improving long-term creep strength is essential for safe operation of plant and equipment. This book provides an authoritative summary of key research in this important area. The first part of the book describes the specifications and manufacture of creep-resistant steels. Part two covers the behaviour of creep-resistant steels and methods for strengthening them. The final group of chapters analyses applications in such areas as turbines and nuclear reactors. With its distinguished editors and international team of contributors, Creep-resistant steels is a valuable reference for the power generation, petrochemical and other industries which use high strength steels at elevated temperatures. Describes the specifications and manufacture of creep-resistant steels Strengthening methods are discussed in detail Different applications are analysed including turbines and nuclear reactors

Resistant

Author:Michael Palmer

Publisher:St. Martin\'s Press

ISBN:1250030900

Total Pages:400

Viewed:381

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They kill without conscience or remorse. They are the most ruthless enemy we have ever faced. And they are one millionth our size...Prepare to be shocked-and mesmerized-by Resistant, the latest novel of thrilling medical suspense from New York Times bestselling author Michael Palmer. When Dr. Lou Welcome fills in last minute for his boss at a national conference in Atlanta he brings along his best friend, Cap Duncan. But an accident turns tragic when Cap injures his leg while running. Surgeons manage to save the leg, but the open wound is the perfect breeding ground for a deadly microbial invader committed to eating Cap alive from the inside out. Meanwhile, hundreds of miles away, a teenaged girl is fighting for her life against the same bacteria. The germ is resistant to any known antibiotic and the government scientist tasked with finding a cure has been kidnapped. Turning to the Centers for Disease Control for help, Lou Welcome uncovers a link to a shadowy group known as One Hundred Neighbors that has infiltrated our society and is using our health institutions as hostages. Like the deadly germs they can unleash, One Hundred Neighbors will stop at nothing to further their agenda. From the hospital corridors where anything you touch can mean your end, to the top corridors of power in this race against time, Lou must stop an epidemic, save his best friend, and face even his own most terrifying demons. From the New York Times bestselling author comes another heart stopping thriller that will make you look at the world around you in a new and frightening way. "When you open the pages of a Michael Palmer novel, you know you are in the hands of a pro." -The Huffington Post

Antibiotic Resistance

Author:Siouxsie Wiles

Publisher:Bridget Williams Books

ISBN:0947518665

Total Pages:136

Viewed:1558

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In ten years’ time, will antibiotics still work? Have we let bacteria get the upper hand in the evolutionary arms race? In the 1920s the discovery of the antibiotic penicillin started a golden age of medicine. However, experts warn that the end of that age may be just a decade away. In this BWB Text, microbiologist Siouxsie Wiles explores the looming crisis of antibiotic resistance and its threat to New Zealand. Wiles concludes that New Zealand must do more to protect the public from a future without antibiotics.

Multigenic and Induced Systemic Resistance in Plants

Author:Tuzun Sadik,Bent Elizabeth

Publisher:Springer Science & Business Media

ISBN:0387232664

Total Pages:522

Viewed:1858

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Plants have developed very sophisticated mechanisms to combat pathogens and pestsusingtheleastamountofreservedorgeneratedenergypossible. Theydothis by activating major defense mechanisms after recognition of the organisms that are considered to be detrimental to their survival; therefore they have been able to exist on Earth longer than any other higher organisms. It has been known for the past century that plants carry genetic information for inherited resistance against many pathogenic organisms including fungi, bacteria, and viruses, and that the relationship between pathogenic organisms and hosts plants are rather complex and in some cases time dependent. This genetic information has been the basis for breeding for resistance that has been employed by plant breeders to develop better-yielding disease resistant varieties, some of which are still being cultivated. Single gene resistance is one type of resistance which has been extensively studied by many research groups all around the world using biotechnological methodologies that have been the subject of many books and journal articles; therefore, it is beyond the scope of this book. This type of resistance is very effective, although it can be overcome by the pressure of pathogenic organisms since it depends on interaction of a single elicitor molecule from the pathogen with a single receptor site in the host.

Improving Genetic Disease Resistance in Farm Animals

Author:Akke Jitske Akkermans,W. Sybesma

Publisher:Springer Science & Business Media

ISBN:9400910576

Total Pages:192

Viewed:1954

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This publication contains the proceedings of a seminar held in Brussels on November 8-9, 1988. The title of the seminar was "Reducing the costs of disease by improving resistance through genetics". The seminar was held as an activity of the Community Programme for the Coordination of Agricultural Research, 1984-1988. Costs of disease depend on losses caused by morbidity, mortality and production decreases and on the costs of preventive measures including vaccination and medication. Production losses often contribute a major portion to the total costs. To reduce costs of disease preventive measures like vaccination, preventive medication and hygienic procedures are applied. Genetic resistance is an attractive preventive measure because of its consistent nature in the next generations, because it precludes veterinary services and because there are no side-effects. Constraints are the long term investment, relatively slow progress per generation (in combination with production traits) and the considerable lack of knowledge about inheritance of resistance mechanisms in farm animals.

Integration of Insect-Resistant Genetically Modified Crops within IPM Programs

Author:Jörg Romeis,Anthony M. Shelton,George Kennedy

Publisher:Springer Science & Business Media

ISBN:1402083734

Total Pages:441

Viewed:1484

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Books Description:

Insect pests remain one of the main constraints to food and fiber production worldwide despite farmers deploying a range of techniques to protect their crops. Modern pest control is guided by the principles of integrated pest management (IPM) with pest resistant germplasm being an important part of the foundation. Since 1996, when the first genetically modified (GM) insect-resistant maize variety was commercialized in the USA, the area planted to insect-resistant GM varieties has grown dramatically, representing the fastest adoption rate of any agricultural technology in human history. The goal of our book is to provide an overview on the role insect-resistant GM plants play in different crop systems worldwide. We hope that the book will contribute to a more rational debate about the role GM crops can play in IPM for food and fiber production.

Breeding Pest-Resistant Trees

Author:H. D. Gerhold,R. E. Mcdermott,E. J. Schreiner

Publisher:Elsevier

ISBN:1483158381

Total Pages:516

Viewed:1462

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Breeding Pest-Resistant Trees documents the proceedings of a N.A.T.O. and N.S.F. Advanced Study Institute on Genetic Improvement For Disease and Insect Resistance of Forest Trees held in Pennsylvania State University from August 30 to September 11, 1964. This book compiles the study and research of geneticists, pathologists, entomologists, and foresters concerned with the genetic resistance of forest trees to pests and breeding programs for disease- and insect-resistant trees. This compilation is divided into three parts. The first part discusses about the résumés of research related to forest tree pest resistance by geographic regions. Part II focuses on the reports of significant research advances in the basic knowledge of disease and insect resistance of forest trees, while Part III includes the discussion of approaches and methods for genetic improvement in pest resistance of forest trees. The topics covered include the variation and inheritance of pest resistance in forest trees; environmental effects on the host-pest relationship; review of basic knowledge of forest tree pest resistance; selection for pest resistance in wild populations; and testing and evaluating inherent pest resistance. This publication is a good source for students and individuals conducting work on the resistance of forest trees to diseases and pest insects.

Renal Denervation

Author:Richard R. Heuser,Markus Schlaich,Horst Sievert

Publisher:Springer

ISBN:1447152239

Total Pages:201

Viewed:867

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Books Description:

Hypertension remains the leading cause of cardiovascular morbidity and mortality in spite of current medical therapies. It has been estimated that 50% of Western civilization has hypertension and approximately 20% of patients have resistant hypertension. Renal denervation (RDN) is a minimally invasive, endovascular catheter based procedure using radiofrequency ablation aimed at treating resistant hypertension. Early studies show a high degree of effectiveness in renal denervation to treat hypertension. This book examines renal pathophysiology and the rationale for renal denervation, as well as possible long term benefits and risks of this new therapy. The myriad of devices involved in the evolution of this therapy are discussed and the book concludes with analyses of the cost effectiveness and future applications.

Evolutionary Ecology

Author:Charles W. Fox,Derek A. Roff,Daphne J. Fairbairn

Publisher:Oxford University Press

ISBN:0198030134

Total Pages:448

Viewed:1976

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Books Description:

Evolutionary Ecology simultaneously unifies conceptual and empirical advances in evolutionary ecology and provides a volume that can be used as either a primary textbook or a supplemental reading in an advanced undergraduate or graduate course. The focus of the book is on current concepts in evolutionary ecology, and the empirical study of these concepts. The editors have assembled a group of prominent biologists who have made significant contributions to this field. They both synthesize the current state of knowledge and identity areas for future investigation. Evolutionary Ecology will be of general interest to researchers and students in both ecology and evolutionary biology. Researchers in evolutionary ecology that want an overview of the current state of the field, and graduate students that want an introduction the field, will find this book very valuable. This volume can also be used as a primary textbook or supplemental reading in both upper division and graduate courses/seminars in Evolutionary Ecology.

Earthquake-Resistant Structures

Author:Mohiuddin Ali Khan

Publisher:Butterworth-Heinemann

ISBN:0080949444

Total Pages:448

Viewed:1001

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Books Description:

Earthquake engineering is the ultimate challenge for structural engineers. Even if natural phenomena involve great uncertainties, structural engineers need to design buildings, bridges, and dams capable of resisting the destructive forces produced by them. These disasters have created a new awareness about the disaster preparedness and mitigation. Before a building, utility system, or transportation structure is built, engineers spend a great deal of time analyzing those structures to make sure they will perform reliably under seismic and other loads. The purpose of this book is to provide structural engineers with tools and information to improve current building and bridge design and construction practices and enhance their sustainability during and after seismic events. In this book, Khan explains the latest theory, design applications and Code Provisions. Earthquake-Resistant Structures features seismic design and retrofitting techniques for low and high raise buildings, single and multi-span bridges, dams and nuclear facilities. The author also compares and contrasts various seismic resistant techniques in USA, Russia, Japan, Turkey, India, China, New Zealand, and Pakistan. Written by a world renowned author and educator Seismic design and retrofitting techniques for all structures Tools improve current building and bridge designs Latest methods for building earthquake-resistant structures Combines physical and geophysical science with structural engineering

Herbicide Resistance in Weeds and Crops

Author:J. C. Caseley,G. W. Cussans,R. K. Atkin

Publisher:Elsevier

ISBN:148310009X

Total Pages:526

Viewed:1509

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Books Description:

Herbicide Resistance in Weeds and Crops is a collection of papers presented at the 11th Long Ashton International Symposium in September 1989. The said symposium is held to study about the increasing incidence of herbicide-resistant weeds and the consideration of the production of herbicide-resistant crops. The book includes studies that suggest the delay and prevention of herbicide resistance; the gravity of the infestation of different herbicide-resistant weed; the management of herbicide resistance; and the mechanisms of herbicide tolerance. Also covered in the book are the improvement of different herbicides, as well as the prospective development of genetically engineered herbicide-resistant plants. Botanists, biochemists, and farmers would greatly benefit from the text, especially those who would like to explore and study the phenomenon.

Growing Resistance

Author:Emily Eaton

Publisher:Univ. of Manitoba Press

ISBN:0887554407

Total Pages:200

Viewed:1007

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Books Description:

In 2004 Candian farmers led an international coalition to a major victory for the anit-GM movement by defeating the introduction of Monsanto's genetically modified wheat. Canadian farmers' strong opposition to GM wheat marked a stark contrast to previous producer acceptance of other genetically modified crops. By 2005, for example, GM canola accounted for 78 percent of all canola grown nationally. So why did farmers stand up for wheat? In Growing Resistance, Emily Eaton reveals the motivating factors behind farmer opposition to GM wheat. She illustrates wheat's cultural, historical, and political significance on the Canadian prairies as well as its role in crop rotation, seed saving practices, and the economic livelihoods of prairie farmers. Through interviews with producers, industry organizations, and biochemical companies, Eaton demonstrates how the inclusion of producer interests was integral to the coalition's success in voicing concerns about environmental implications, international market opposition to GMOs, and the lack of transparency and democracy in Canadian biotech policy and regulation. Growing Resistance is a fascinating study of successful coalition building, of the need to balance local and global concerns in activist movements, and of the powerful forces vying for control of food production.

Antibiotic Resistant Bacteria: A Challenge to Modern Medicine

Author:Sadhana Sagar,Shilpa Kaistha,Amar Jyoti Das,Rajesh Kumar

Publisher:Springer Nature

ISBN:9811398798

Total Pages:179

Viewed:748

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Books Description:

This book summarizes the emerging trends in the field of antibiotic resistance of various gram-negative and gram-positive bacterial species. The ability of different species of bacteria to resist the antimicrobial agent has become a global problem. As such, the book provides a comprehensive overview of the advances in our understanding of the origin and mechanism of resistance, discusses the modern concept of the biochemical and genetic basis of antibacterial resistance and highlights the clinical and economic implications of the increased prevalence of antimicrobial resistant pathogens and their ecotoxic effects. It also reviews various strategies to curtail the emergence and examines a number of innovative therapeutic approaches, such as CRISPR, phage therapy, nanoparticles and natural antimicrobials, to combat the spread of resistance.

Fire- and Smoke-Resistant Interior Materials for Commercial Transport Aircraft

Author:National Research Council,Division on Engineering and Physical Sciences,National Materials Advisory Board,Commission on Engineering and Technical Systems,Committee on Fire and Smoke Resistant Materials for Commercial Aircraft Interiors

Publisher:National Academies Press

ISBN:0309175933

Total Pages:82

Viewed:997

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Books Description:

The two principal objectives of this book were (1) to identify promising materials technologies, design issues (both overall and for individual components), and fire performance parameters (both full scale and for individual components) that, if properly optimized, would lead to improved fire and smoke resistance of materials and components used in aircraft interiors; and (2) to identify long-range research directions that hold the most promise for producing predictive modeling capability, new advanced materials, and the required product development to achieve totally fire-resistant interiors in future aircrafts. The emphasis of the study is on long-term innovation leading to impacts on fire worthiness of aircraft interiors ten to twenty years hence.

Heat-Resistant Polymers

Author:J.P. Critchley,G.J. Knight,W.W. Wright

Publisher:Springer Science & Business Media

ISBN:1489903968

Total Pages:403

Viewed:1012

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Books Description:

Definitions of what is meant by a heat-resistant polymer vary considerably. We have taken the term to mean a polymer which can be used, at least for short time periods, at temperatures from 150°C. The greatest problem which arises in writing a monograph on such materials is the tremendous amount of data that is available. More than 2000 references have been published on one heat-resistant polymer system alone over a period of little more than two years. The result is that a very high degree of selectivity must be exercised with respect to the information reproduced. We have chosen to restrict our coverage to polymers that have received at least some degree of commercial exploitation and to details of their methods of preparation, their thermal and thermo-oxidative stabilities and modes of degradation, and their properties at elevated temperatures. It must be emphasized that other properties not cited, e. g. , hydrolytic and chemical stability, and resistance to ultraviolet radiation, may be equally important in particular uses of these materials. The "older" heat-resistant polymers, e. g. , the thermosets and some of the fluorine-containing materials, are not dealt with in such depth as are the "newer" polymers with aromatic and/or heterocyclic rings in the chain. This is because books have been available for some time on the well-established commercial polymers and developments in them have not been as marked re cently as in the aromatic and heterocyclic macromolecules.